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High-Performance Protein Thermal Stability Profiling

Differential Scanning Fluorimetry services with unprecedented versatility, sensitivity, and throughput

Realizing the full potential of DSF

Despite being a widely used technique for determining the apparent melting temperature of a purified protein, DSF has largely been treated as a secondary use case in the development of most high throughput thermal profiling technologies. At S32 Labs, we're building a first-class DSF High Throughput Screening Platform to realize the full potential of this well regarded in vitro technique.   

Increased versatility

Our proprietary sets of hardware and software interfaces enable dye profiling and ligand screening with fluorescence from near-UV to near-IR wavelengths 

Decreased reagent input

design assays with <5 uL reactions and protein concentrations <1 uM

Increased sensitivity

Precise fluorescence excitation and detection reduces background, while high dynamic range boosts intensity resolution

Increased Data Transparency

Access your raw fluorescent intensity readings on a transparent absolute scale, increasing insights into assay dynamics and readiness for Machine Learning

Differential Scanning Fluorimetry, 
Supercharged.

Discover how our advanced protein stability analysis services can propel your biotech endeavors to new heights.

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